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HOW Collaborative Issues

HOW Collaborative Medical Conditions

The following is a non-exhaustive list of ‘HOW Collaborative Medical Conditions’ and require a multidisciplinary approach to optimise patient care.
Women with pre-existing haematological disorders which require specific management during pregnancy or impact on issues specific to women such as heavy menstrual bleeding or fertility

Increased venous thromboembolism risk

  • Previous venous thromboembolism
  • Inherited or acquired thrombophilia

Anticoagulation planning

  • Patients on long term anticoagulation

Haematology malignancy

  • Acute and chronic leukaemia
  • Hodgkin and Non-Hodgkin Lymphoma
  • Myeloproliferative neoplasm

Haemoglobinopathy / Red cell disorders

  • Sickle cell disease
  • Thalassaemia
    • Transfusion-Dependent Thalassaemia
    • Non-Transfusion-Dependent Thalassaemia
    • Haemoglobin H disease

Bleeding disorders

  • Immune thrombocytopenia
  • Haemophilia
  • von Willebrand disease
  • Rare bleeding disorders (e.g. factor VII, XI deficiency)
  • Platelet disorders
Women with pregnancy-associated haematological conditions

Gestational thrombocytopenia

Neonatal alloimmune thrombocytopenia (NAIT)

Acute postpartum haemorrhage

Haemolytic disease of the fetus and newborn (HDFN)

Pregnancy associated thrombotic microangiopathy

  • HELLP
  • Thrombotic thrombocytopenic purpura (TTP)

Anaemia

  • Iron deficiency anaemia (also a complication of heavy menstrual bleeding outside of pregnancy)
Transfusion and laboratory issues

Patients who are unable to receive or decline transfusion of blood components (e.g. Jehovah’s Witnesses)

Interpretation of haemoglobinopathy testing

Women with haematological complications related to gynaecological treatment such as hormone associated thrombosis

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